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1

Discovery of Ritonavir, a Potent Inhibitor of HIV Protease with High Oral Bioavailability and Clinical Efficacy

Kempf, Dale J., Sham, Hing L., Marsh, Kennan C., Flentge, Charles A., Betebenner, David, Green, Brian E., McDonald, Edith, Vasavanonda, Sudthida, Saldivar, Ayda, Wideburg, Norman E., Kati, Warren M.,

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

2

Factors influencing speech perception in the context of a merger-in-progress

Jennifer Hay, Paul Warren, Katie Drager

Journal:

Journal of Phonetics

Year:

2006

Language:

english

File:

PDF, 675 KB

english, 2006

3

The Inflammatory Response to Cardiopulmonary Bypass: Part 2—Anti-Inflammatory Therapeutic Strategies

Oliver J. Warren, Amy L. Watret, Katie L. de Wit, Christos Alexiou, Charles Vincent, Ara W. Darzi, Thanos Athanasiou

Journal:

Journal of Cardiothoracic and Vascular Anesthesia

Year:

2009

Language:

english

File:

PDF, 481 KB

english, 2009

4

Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human

Mark S. Warren, Noa Zerangue, Katie Woodford, Lori M. Roberts, Emily H. Tate, Bo Feng, Cheryl Li, Thomas J. Feuerstein, John Gibbs, Bill Smith, Sonia M. de Morais, William J. Dower, Kerry J. Koller

Journal:

Pharmacological Research

Year:

2009

Language:

english

File:

PDF, 800 KB

english, 2009

5

The Association Between Contraceptive Use at theTime of Conception and Hypertensive DisordersDuring Pregnancy: A Retrospective Cohort Study ofPrams Participants

Farley, Katie E., Huber, Larissa R. Brunner, Warren-Findlow, Jan, Ersek, Jennifer L.

Journal:

Maternal and Child Health Journal

Year:

2014

Language:

english

File:

PDF, 195 KB

english, 2014

6

Understanding, teaching and assessing the elements of the CanMEDS Professional Role: Canadian Program Directors’ views

Warren, Andrew E., Allen, Victoria M., Bergin, Fiona, Hazelton, Lara, Alexiadis-Brown, Peggy, Lightfoot, Katie, McSweeney, Jill, Singleton, Jerome F., Sargeant, Joan, Mann, Karen

Journal:

Medical Teacher

Year:

2014

Language:

english

File:

PDF, 229 KB

english, 2014

7

Germline RAD51C mutations confer susceptibility to ovarian cancer

Loveday, Chey, Turnbull, Clare, Ruark, Elise, Xicola, Rosa Maria Munoz, Ramsay, Emma, Hughes, Deborah, Warren-Perry, Margaret, Snape, Katie, Eccles, Diana, Evans, D Gareth, Gore, Martin, Renwick, Anth

Journal:

Nature Genetics

Year:

2012

Language:

english

File:

PDF, 123 KB

english, 2012

8

An MRI Investigation Into the Function of the Transversus Abdominis Muscle During “Drawing-In” of the Abdominal Wall

Hides, Julie, Wilson, Stephen, Stanton, Warren, McMahon, Shaun, Keto, Heidi, McMahon, Katie, Bryant, Martina, Richardson, Carolyn

Journal:

Year:

2006

Language:

english

File:

PDF, 493 KB

english, 2006

9

Early deprivation disruption of associative learning is a developmental pathway to depression and social problems

Sheridan, Margaret A., McLaughlin, Katie A., Winter, Warren, Fox, Nathan, Zeanah, Charles, Nelson, Charles A.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 729 KB

english, 2018

10

Anxiety and Interpretation of Ambiguity in Autistic Children, Typical Children and Their Mothers

Neil, Louise, White, Hannah, Warren, Katy, Pellicano, Elizabeth

Journal:

Journal of Autism and Developmental Disorders

Year:

2018

Language:

english

File:

PDF, 915 KB

english, 2018

11

Design, Synthesis, and Neuraminidase Inhibitory Activity of GS-4071 Analogues that Utilize a Novel Hydrophobic Paradigm.

Stephen Hanessian, Jianchio Wang, Debra Montgomery, Vincent Stoll, Kent D. Steward, Warren Kati, Clarence Maring, Dale Kempf, Charles Hutchins, W. Graeme Laver

Journal:

Year:

2003

File:

PDF, 147 KB

2003

12

A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctions

Michaella Velichkova, Julian Guttman, Carmen Warren, Lily Eng, Katie Kline, A. Wayne Vogl, Tama Hasson

Journal:

Year:

2002

Language:

english

File:

PDF, 3.32 MB

english, 2002

13

Use of a Fluorescence Plate Reader for Measuring Kinetic Parameters with Inner Filter Effect Correction

Yaya Liu, Warren Kati, Chih-Ming Chen, Rakesh Tripathi, Akhter Molla, William Kohlbrenner

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 70 KB

english, 1999

14

Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors

John T. Randolph, Peggy P. Huang, William J. Flosi, David DeGoey, Larry L. Klein, Clinton M. Yeung, Charles Flentge, Mingua Sun, Chen Zhao, Tatyana Dekhtyar, Hongmei Mo, Lynn Colletti, Warren Kati, Ke

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 268 KB

english, 2006

15

Synthesis, antiviral activity, and conformational studies of a P3 aza-peptide analog of a potent macrocyclic tripeptide HCV protease inhibitor

John T. Randolph, Xiaolin Zhang, Peggy P. Huang, Larry L. Klein, Kevin A. Kurtz, Alex K. Konstantinidis, Wenping He, Warren M. Kati, Dale J. Kempf

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 436 KB

english, 2008

16

A fluorescence polarization-based assay for peptidyl prolyl cis/trans isomerase cyclophilin A

Yaya Liu, Jianjun Jiang, Paul L. Richardson, Rajarathnam D. Reddy, Donald D. Johnson, Warren M. Kati

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 373 KB

english, 2006

17

Longer wavelength fluorescence resonance energy transfer depsipeptide substrates for hepatitis C virus NS3 protease

Alex K. Konstantinidis, Paul L. Richardson, Kevin A. Kurtz, Rakesh Tripathi, Chih-Ming Chen, Peggy Huang, John Randolph, Danli Towne, Jennifer Donnelly, Usha Warrior, Tim Middleton, Warren M. Kati

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

18

Methods to measure the intracellular concentration of unlabeled compounds within cultured cells using liquid chromatography/tandem mass spectrometry

Lynn M. Colletti, Yaya Liu, Gennadiy Koev, Paul L. Richardson, Chih-Ming Chen, Warren Kati

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 246 KB

english, 2008

19

Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core

Gary T. Wang, Sheldon Wang, Robert Gentles, Thomas Sowin, Clarence J. Maring, Dale J. Kempf, Warren M. Kati, Vincent Stoll, Kent D. Stewart, Graeme Laver

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 308 KB

english, 2005

20

Inhibitors of HCV NS5B polymerase: synthesis and structure–activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines

John K. Pratt, Pamela Donner, Keith F. McDaniel, Clarence J. Maring, Warren M. Kati, Hongmei Mo, Tim Middleton, Yaya Liu, Teresa Ng, Qinghua Xie, Rong Zhang, Debra Montgomery, Akhteruzzaman Molla, Dal

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

21

Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring

Todd W. Rockway, Rong Zhang, Dachun Liu, David A. Betebenner, Keith F. McDaniel, John K. Pratt, David Beno, Debra Montgomery, Wen W. Jiang, Sherie Masse, Warren M. Kati, Tim Middleton, Akhteruzzaman M

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

22

Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives

A. Chris Krueger, Darold L. Madigan, Brian E. Green, Douglas K. Hutchinson, Wen W. Jiang, Warren M. Kati, Yaya Liu, Clarence J. Maring, Sherie V. Masse, Keith F. McDaniel, Tim R. Middleton, Hongmei Mo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 145 KB

english, 2007

23

Synthesis and SAR of novel 1,1-dialkyl-2(1H)-naphthalenones as potent HCV polymerase inhibitors

Todd D. Bosse, Daniel P. Larson, Rolf Wagner, Doug K. Hutchinson, Todd W. Rockway, Warren M. Kati, Yaya Liu, Sherie Masse, Tim Middleton, Hongmei Mo, Debra Montgomery, Wen Jiang, Gennadiy Koev, Dale J

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 147 KB

english, 2008

24

Synthesis of potent pyrrolidine influenza neuraminidase inhibitors

A. Chris Krueger, Yibo Xu, Warren M. Kati, Dale J. Kempf, Clarence J. Maring, Keith F. McDaniel, Akhteruzzaman Molla, Debra Montgomery, William E. Kohlbrenner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 135 KB

english, 2008

25

Des-A-ring benzothiadiazines: Inhibitors of HCV genotype 1 NS5B RNA-dependent RNA polymerase

Pamela L. Donner, Qinghua Xie, John K. Pratt, Clarence J. Maring, Warren Kati, Wen Jiang, Yaya Liu, Gennadiy Koev, Sherie Masse, Debra Montgomery, Akhter Molla, Dale J. Kempf

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 185 KB

english, 2008

26

Identification of halosalicylamide derivatives as a novel class of allosteric inhibitors of HCV NS5B polymerase

Yaya Liu, Pamela L. Donner, John K. Pratt, Wen W. Jiang, Teresa Ng, Vijaya Gracias, Steve Baumeister, Paul E. Wiedeman, Linda Traphagen, Usha Warrior, Clarence Maring, Warren M. Kati, Stevan W. Djuric

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

27

Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives

Douglas K. Hutchinson, Teresa Rosenberg, Larry L. Klein, Todd D. Bosse, Daniel P. Larson, Wenping He, Wen W. Jiang, Warren M. Kati, William E. Kohlbrenner, Yaya Liu, Sherie V. Masse, Tim Middleton, Ak

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

28

Benzimidazole- and indole-substituted 1,3′-bipyrrolidine benzamides as histamine H3 receptor antagonists

Derek C. Cole, Jonathan L. Gross, Thomas A. Comery, Suzan Aschmies, Warren D. Hirst, Cody Kelley, Ji-In Kim, Katie Kubek, Xiaoping Ning, Brian J. Platt, Albert J. Robichaud, William R. Solvibile, Jose

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 523 KB

english, 2010

29

Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moiety

Douglas K. Hutchinson, Charles A. Flentge, Pamela L. Donner, Rolf Wagner, Clarence J. Maring, Warren M. Kati, Yaya Liu, Sherie V. Masse, Tim Middleton, Hongmei Mo, Debra Montgomery, Wen W. Jiang, Genn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 410 KB

english, 2011

30

Design, synthesis, and neuraminidase inhibitory activity of GS-4071 analogues that utilize a novel hydrophobic paradigm

Stephen Hanessian, Jianchio Wang, Debra Montgomery, Vincent Stoll, Kent D. Stewart, Warren Kati, Clarence Maring, Dale Kempf, Charles Hutchins, W.Graeme Laver

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

31

Corrigendum to ‘Design, Synthesis, and Neuraminidase Inhibitory Activity of GS-4071 Analogues that Utilize a Novel Hydrophobic Paradigm’: [Bioorg. Med. Chem. Lett. 12 (2002) 3425]

Stephen Hanessian, Jianchio Wang, Debra Montgomery, Vincent Stoll, Kent D. Stewart, Warren Kati, Clarence Maring, Dale Kempt, Charles Hutchins, W.Graeme Laver

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 77 KB

english, 2003

32

Familial adenomatous polyposis complicated by an intrahepatic desmoid tumor

Simon B. Middleton, Katy Fidler, Warren Hyer, Robin K. S. Phillips

Journal:

Diseases of the Colon & Rectum

Year:

2000

Language:

english

File:

PDF, 259 KB

english, 2000

33

Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides

A. Chris Krueger, Darold L. Madigan, Wen W. Jiang, Warren M. Kati, Dachun Liu, Yaya Liu, Clarence J. Maring, Sherie Masse, Keith F. McDaniel, Tim Middleton, Hongmei Mo, Akhteruzzaman Molla, Debra Mont

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 121 KB

english, 2006

34

Production, purification and functional validation of human secreted amyloid precursor proteins for use as neuropharmacological reagents

Paul R. Turner, Katie Bourne, Daniel Garama, Alan Carne, Wickliffe C. Abraham, Warren P. Tate

Journal:

Journal of Neuroscience Methods

Year:

2007

Language:

english

File:

PDF, 481 KB

english, 2007

35

Signals that Initiate, Augment, and Provide Directionality for Human Keratinocyte Motility

Li, Wei, Henry, Ginard, Fan, Jianhua, Bandyopadhyay, Balaji, Pang, Katie, Garner, Warren, Chen, Mei, Woodley, David T.

Journal:

The Journal of Investigative Dermatology

Year:

2004

Language:

english

File:

PDF, 1.35 MB

english, 2004

36

Oral glucose tolerance testing in children with cystic fibrosis

Katie Larson Ode, Brigitte Frohnert, Theresa Laguna, James Phillips, Bonnie Holme, Warren Regelmann, William Thomas, Antoinette Moran

Journal:

Pediatric Diabetes

Year:

2010

Language:

english

File:

PDF, 536 KB

english, 2010

37

Variations in the Application of Various Perfusion Technologies in Great Britain and Ireland—A National Survey

Oliver J. Warren, Sophie Wallace, Katie L. De Wit, Charles Vincent, Ara W. Darzi, Thanos Athanasiou

Journal:

Artificial Organs

Year:

2010

Language:

english

File:

PDF, 217 KB

english, 2010

38

A longitudinal study of dental caries risk among very young low SES children

John J. Warren, Karin Weber-Gasparoni, Teresa A. Marshall, David R. Drake, Farideh Dehkordi-Vakil, Deborah V. Dawson, Katie M. Tharp

Journal:

Community Dentistry and Oral Epidemiology

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

39

BMD at Multiple Sites and Risk of Fracture of Multiple Types: Long-Term Results From the Study of Osteoporotic Fractures

Katie L Stone, Dana G Seeley, Li-Yung Lui, Jane A Cauley, Kristine Ensrud, Warren S Browner, Michael C Nevitt, Steven R Cummings

Journal:

Journal of Bone and Mineral Research

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

40

DDE-induced changes in aromatase activity in endometrial stromal cells in culture

Alison C. Holloway, Katie A. Stys, Warren G. Foster

Journal:

Endocrine (Springer)

Year:

2005

Language:

english

File:

PDF, 245 KB

english, 2005

41

Mechanistic Study of HCV Polymerase Inhibitors at Individual Steps of the Polymerization Reaction

Liu, Yaya, Jiang, Wen W., Pratt, John, Rockway, Todd, Harris, Kevin, Vasavanonda, Sudthida, Tripathi, Rakesh, Pithawalla, Ron, Kati, Warren M.

Journal:

Year:

2006

Language:

english

File:

PDF, 792 KB

english, 2006

42

In vivo biostability of polyurethane–organosilicate nanocomposites

Katie E. Styan, Darren J. Martin, Anne Simmons, Laura A. Poole-Warren

Journal:

Acta Biomaterialia

Year:

2012

Language:

english

File:

PDF, 2.01 MB

english, 2012

43

Inhibition of human immunodeficiency virus type I integrase by naphthamidines and 2-aminobenzimidazoles

Tim Middleton, Hock B. Lim, Debra Montgomery, Todd Rockway, Hua Tang, Xueheng Cheng, Liangjun Lu, Hongmei Mo, William E. Kohlbrenner, Akhteruzzaman Molla, Warren M. Kati

Journal:

Antiviral Research

Year:

2004

Language:

english

File:

PDF, 302 KB

english, 2004

44

Replication efficiency of chimeric replicon containing NS5A–5B genes derived from HCV-infected patient sera

Rakesh L. Tripathi, Preethi Krishnan, Yupeng He, Tim Middleton, Tami Pilot-Matias, Chih-Ming Chen, Daryl T.Y. Lau, Stanley M. Lemon, Hongmei Mo, Warren Kati, Akhteruzzaman Molla

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 741 KB

english, 2007

45

Identification of Halosalicylamide Derivatives as a Novel Class of Allosteric Inhibitors of HCV NS5B Polymerase

Yaya Liu, Pamela Donner, Wen Jiang, Teresa Ng, Vijaya Gracias, Steve Baumeister, Paul Wiedeman, Linda Traphagen, Usha Warrior, Clarence Maring, Warren Kati, Stevan Djuric, Akhteruzzaman Molla

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

46

Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well

Rubina Mondal, Gennadiy Koev, Tami Pilot-Matias, Yupeng He, Teresa Ng, Warren Kati, Akhteruzzaman Molla

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 601 KB

english, 2009

47

The Discovery and Efficacy of a Small Molecule Inhibitor of Ebola Capsid Assembly in an Animal Model

Jean Francis, Warren Kalina, Travis Warren, Katie Edwards, I-ting Jaing, A. Pia Abola, Abhar Nissar, Anatoliy Kitaygorodskyy, Clarence R. Hurt, Sina Bavari, William Hansen, Vishwanath R. Lingappa

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 90 KB

english, 2010

48

Identification of aryl dihydrouracil derivatives as palm initiation site inhibitors of HCV NS5B polymerase

Yaya Liu, Ben Hock Lim, Wen W. Jiang, Charles A. Flentge, Douglas K. Hutchinson, Darold L. Madigan, John T. Randolph, Rolf Wagner, Clarence J. Maring, Warren M. Kati, Akhteruzzaman Molla

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 474 KB

english, 2012

49

Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

Chanel J. Taylor, David R. Ireland, Irene Ballagh, Katie Bourne, Nicola M. Marechal, Paul R. Turner, David K. Bilkey, Warren P. Tate, Wickliffe C. Abraham

Journal:

Neurobiology of Disease

Year:

2008

Language:

english

File:

PDF, 1.24 MB

english, 2008

50

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

Hongmei Mo, Alex K. Konstantinidis, Kent D. Stewart, Tatyana Dekhtyar, Teresa Ng, Kerry Swift, Edmund D. Matayoshi, Warren Kati, William Kohlbrenner, Akhteruzzaman Molla

Journal:

Year:

2004

Language:

english

File:

PDF, 305 KB

english, 2004